This year marks the first iteration of the BaCell3D conference. The conference focuses on how organoid and organ-on-a-chip technologies can be used to recapitulate development or regeneration, and how these model systems can be used for disease modelling, drug discovery, and personalised medicine. We look forward to exciting talks (including keynotes from Nicolas Rivron and Kara McKinley), refreshing discussions, and for many of us the first in-person meeting after the long break!