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Prisca Liberali

Prisca has been trained as a physical organic chemist with a focus on the dynamical understanding of organic chemical reactions. She then changed fields for her PhD and became a molecular cell biologist. She has developed single-cell methods to study cell-to-cell variability and its involvement in the emergence of complex cellular traits. Since a few years she has become fascinated by the role of self-organisation in collective cell behaviours , and how these can control intracellular signalling in single cells. Because these emergent phenomena have multiple layers of biological organisation at different scales, she believes that novel experimental, quantitative and statistical methods are required to integrate our understanding of single-cell biology. Currently, she is an assistant professor at the FMI with a lab focused on dynamics of self-organisation, and how cellular signalling dictates its spatial-temporal regulation.

 
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Dario Vischi

Dario joined the lab as a research associate in October 2017. He obtained his master’s degree in Engineering with a specialization in Digital Image Processing at the University of Applied Sciences Northwestern Switzerland. During his master thesis, he developed a high-performance image-processing pipeline for the automatic detection and analysis of tumor tissue in prostate punch biopsies. The following two years, he worked at the Institute of 4D Technologies where he taught students and developed systems to analyze and process satellite data.

His goal is to involve people as early as possible and as much as possible in the software development process to build software one can really use.

 
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Denise Serra

Denise joined the lab as PhD student in November 2015. She obtained her Master’s degree in Biology from the University Milano Bicocca, Italy. 

She is interested in characterizing mechanisms and signalling pathways driving self-organization and symmetry breaking in intestinal organoid development.

 
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Francisca Maurer

Francisca joined the lab when it started in July 2015. She worked as  lab manager for 32 years at FMI in cancer research, and now as the lab manager of the group. She obtained her Bachelor of Science in Medical technology from the Pontifical University of Santo Tomas in the Philippines.

 
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Gustavo Quintas Glasner de Medeiros

Gustavo did his PhD work on deep tissue light-sheet microscopy at the European Molecular Biology Laboratory in Heidelberg, and started in the lab as a Postdoctoral fellow in January 2018.

His main interests are in the development of imaging and perturbation methods which allow an in-depth study of the dynamics behind symmetry-breaking during intestinal organoid growth.

 
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Ilya Lukonin

Ilya was born and grew up in Tallinn, Estonia before moving to Berlin where he got his Bachelor and Master degrees in Biochemistry. Since he joined the lab in July 2015, Ilya is using high content imaging to map the functional interactions shaping intestinal organoid development and homeostasis.

 
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Ludivine Challet Meylan

Ludivine joined the lab as a technical/research associate in January 2018. She obtained her PhD in neurogenetic from the University of Geneva in 2012. She then studied vascular disorders using stem cell and genome engineering technologies as a SNSF postdoctoral fellow at Harvard University.

Her current tasks include implementing new protocols and techniques for the lab and establishing projects involving human organoids.

 
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Marietta Zinner

Marietta joined the lab as PhD student in May 2016. She obtained her Master’s degree in Molecular Biology from the University of Vienna, Austria.

She aims to understand how the acquisition of neural fate is coordinated during embryogenesis using human neuroepithelial organoids and mouse gastruloids.

 
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Markus Rempfler

Markus holds a Master's degree in biomedical engineering from ETH
Zürich and a doctoral degree in computer science from TU München. He joined FMI in 2018 as machine learning specialist, where he develops algorithms for biomedical image analysis in close collaboration with the research labs.

 
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Qiutan Yang

Qiutan did her PhD in University of Zurich with the focus on epithelial morphogenesis during development.  She joined Liberali lab as a Postdoctoral fellow in August 2017 where she is using intestinal stem-cell-derived organoids as model system to investigate the morphogenetic rearrangement and self-organization in mammalian tissue development and regeneration.

 
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Raphael Ortiz

Raphael earned his MSc in Electrical and Electronic Engineering from École polytechnique fédérale de Lausanne (EPFL). In 2013, he moved to Singapore and started research work on microfluidic biosensor for micropollutants detection in water and was awarded his PhD from Nanyang Technological University (NTU) in 2018. In January 2019, Raphael started as as machine-learning expert in the lab where he develops novel techniques for bio-image analysis.

 
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Urs Mayr

Urs received his Masters’s degree in Systems Biology from ETH Zurich. He joined the lab as PhD student in August 2016 to study how cell-to-cell variability drives emergent behaviours of populations of cells. In particular, he is interested in the role of cell-to-cell variability during symmetry breaking in intestinal organoid formation.

 

MASTER STUDENTS

Robin Rothenfluh

 

Alumni

Aline Xavier da Silveira dos Santos, Postdoctoral fellow (2015-2019)
Anna Bailach Adsuara, Undergraduate student (2018-2019)
Andrea Boni, Postdoctoral fellow (2016-2017)
Claudia Keller, Undergraduate student (2017, 2018)
Jacqueline Staehlin, Undergraduate student (2015-2016)
Katrin Volkmann, Imaging associate (2015-2018)
Saadia Iftikhar, Computational associate (2015-2017)
Stefan Uhlmann, Postdoctoral fellow (2015)